CRYOABLATION

|arrhythmia|arrhythmia|heart arrhythmia|cardiac arrhythmias An organization may jump out front with a revolutionary idea, but the
only way to stay there is to expand successfully on all fronts. Building on its groundbreaking research, CryoCath has grown to become a well-funded, market-driven corporation. Already successful in major European and Rest-of-World (ROW) markets, CryoCath is extending its leadership to the United States through growing sales of SurgiFrost™ and Freezor® products. CryoCath established its pre-eminence in catheter-based CryoTherapy products for the electrophysiology ablation market with its first commercial product, Freezor®. CryoCath now serves a second major worldwide customer base, cardiac surgeons, with its unique SurgiFrost™ Surgical CryoAblation System for the treatment of cardiac arrhythmias. CryoCath continues to focus on expanding the distribution and use of both product families to existing and new key markets throughout the world.

CryoCath probes look and feel similar to heat-based probes, but do not
destroy tissue in the same manner. The prolonged use of very cold
temperatures results in a lethal injury to target tissue. The
mechanisms of CryoTherapy are largely seen at the cellular level, where
subfreezing temperatures induce both intracellular and extracellular
ice crystal formation. The extracellular fibrous matrix, largely
composed of anhydrous components containing components such as elastin and collagen, remains largely unaffected by ice crystal formation.
Consequently, tissue CryoAblation can be performed without damage to
the underlying structure of the heart.

Cryoablation induces necrosis of myocardial fibers but spares the collagenous framework. The chronic scar is made of dense fibrotic tissue that has no tendency to rupture or dilate.”CryoAblation is well suited in the pericardial space as this area has no blood flow. Thanks to CryoAdhesion, the device tip sticks to the epicardium during the ablation procedure, resulting in enhanced stability.

Cryoablation is a safe and effective technique for AVNRT ablation. It
may be useful particularly when the ablation must be performed close to
the atrioventricular node or HIS bundle, due to the possibility of
validating the site of ablation by means of ice mapping....”
Cryoablation is as effective and safe as RF ablation, [with] significantly less applications…. This supports the use for cryoablation in the treatment of tachyarrhythmias in close proximity to the compact AV node.”

CRYOABLATION – KEY ATTRIBUTES

  • Intact endothelium significantly reduces likelihood of thrombus

  • Collagen matrix remains intact

  • Cryoablation has the potential of avoiding stenosis of the pulmonary veins (PV)4

  • The use of power sources other than radio frequency (RF) appears to greatly reduce, or perhaps eliminate, the risk of PV stenosis4

  • No burning or charring





cryoablation |
arrhythmia | atrial flutter | cryotherapy | heart arrhythmia | atrial fibrillation treatment | cardiac ablation | catheter ablation | cardiac arrhythmias | cryoablation | atrial fibrillation |