Articles and abstracts
Pre-clinical and clinical experience reported in published papers has demonstrated the safety and effectiveness of CryoTherapy. Studies have demonstrated the unique characteristics of CryoTherapy, including electrical reversibility, unparalleled catheter stability, reduced risk of thrombosis and stenosis, and the preservation of tissue integrity. Clinical Experience has also confirmed the safety of CryoMapping and CryoAblation around critical or delicate structures of the heart, such as the AV node and pulmonary veins.
For details on the efficacy and safety of CryoTherapy in the clinical treatment of arrhythmias, consult the papers or abstracts listed below.
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2008
2007
2006
2005
Blaufox, Andrew "Catheter Ablation of Tachyarrhythmias in Small Children" (journal)
Pediatric clinical experience
Chan et al. "Initial Experience of Catheter Cryoablation and Cryomapping for Arrhythmias" (journal)
Clinical Experience
Collins et al. "Cryoablation Versus Radiofrequency Ablation in the Treatment of Atrial Flutter Trial (CRAAFT)" (abstract)
Pediatric clinical experience
De Ponti, Roberto "Cryothermal Energy Ablation of Cardiac Arrhythmias 2005: State of the Art" (journal)
Clinical Experience
Doshi et al. "The Additive Efficacy of a Novel Balloon Cryoablation Catheter to Standard Cryoablation for PV Isolation in Patients with Symptomatic Atrial Fibrillation" (abstract)
Clinical Experience
Drago et al. "Transvenous Cryothermal Catheter Ablation of Re-Entry Circuit Located Near the Atrioventricular Junction in Pediatric Patients" (journal)
Pediatric clinical experience
Etheridge, Susan P. "Cryoablation for Supraventricular Tachycardia in Children: Is It Okay to Trade Success for Decreased Risk?" (journal)
Pediatric clinical experience
Evonich et al. "A Randomized Trial Comparing Effects of Radiofrequency and Cryoablation on the Structural Integrity of Esophageal Tissue" (abstract)
Pre-clinical experience
Friedman, Peter L. "Catheter Cryoablation of Cardiac Arrhythmias " (journal)
AVNRT
Clinical Experience
Friedman, Peter L. "How to ablate atrioventricular nodal reentry using cryoenergy" (journal)
AVNRT
Clinical Experience
Greiss et al. "Incidence of Pulmonary Vein Stenosis After Pulmonary Vein Isolation by Use of Cryoenergy in Patients with Therapy-refractory Atrial Fibrillation in the Long-term Course" (abstract)
Clinical Experience
Greiss et al. "Slow Pathway Ablation for AVNRT: a Comparison Between Cryoablation and Radiofrequency Energy in a 5-year Experience" (abstract)
Clinical Experience
Kettering et al. "Atrial Linear Lesions: Feasibility Using Cryoablation" (abstract)
Pre-clinical experience
Kirsh et al. "Catheter Cryoablation of Pediatric AVNRT: are there Predictors of Success, Failure and Recurrence?" (abstract)
Pediatric clinical experience
Kirsh et al. "Transcatheter Cryoablation of Tachyarrhythmias in Children: Initial Experience from an International Registry" (journal)
Pediatric clinical experience
Kriebel et al. "Efficacy and Safety of Cryoenergy in the Ablation of Atrioventricular Reentrant Tachycardia Substrates in Children and Adolescents " (journal)
Pediatric clinical experience
Kuniss et al. "Persistancy of Bidirectional Conduction Block in the Cavotricuspid Isthmus One Month After Cryocatheter Ablation (8mm-tip) of Common Atrial Flutter" (abstract)
Clinical Experience
Kurzidim et al. "Cryocatheter Ablation of Right Ventricular Outflow Tract Tachycardia" (journal)
Clinical Experience
Mahapatra et al. "Absence of Pulmonary Vein Stenosis Following Balloon Cryo-ablation on Long-term CT Assessment in a Canine Model" (abstract)
Pre-clinical experience
Miyazaki et al. "Cryo-Ablation for Septal Tachycardia Substrates in Pediatric Patients: Mid-Term Results" (journal)
Pediatric clinical experience
Miyazaki et al. "Prolongation of the fast pathway effective refractory period during cryoablation in children: A marker of slow pathway modification" (journal)
Pediatric clinical experience
Montenero et al. "Comparison Between a 7 French 6mm-tip Cryothermal Catheter and a 9 French 8mm-tip Cryothermal Catheter for Cryoablation Treatment of Common Atrial Flutter" (journal)
Clinical Experience
Montenero et al. "Cryothermal Ablation Treatment of Atrial Flutter - Experience with a New 9 French 8mm-tip Catheter" (journal)
Clinical Experience
Montenero et al. "Long-Term Efficacy of Cryo Catheter Ablation for the Treatment of Atrial Flutter: Results From a Repeat Electrophysiologic Study" (journal)
Clinical Experience
Nakagawa et al. "Comparison of Cryothermia and Radiofrequency Current in Safety and Efficacy of Catheter Ablation within the Canine Coronary Sinus Close to the Left Circumflex Coronary Artery" (journal)
Pre-clinical experience
Neuzil et al. "Use of Intracardiac Ultrasound to Guide Balloon Catheter Cryoablation of the Left Atrial-Pulmonary Venous Junction: Determinants of Ablation Efficacy" (abstract)
Clinical Experience
Novak et al. "Persistent Dual AV Nodal Physiology with Tachycardia Non-inducibility Post Slow Pathway Ablation Does Not Predict Arrhythmia Recurrences Following Cryoablation for AVNRT" (abstract)
Clinical Experience
Pitschner et al. "Pulmonary vein isolation in patients with atrial fibrillation using a novel balloon cryoablation catheter" (abstract)
Clinical Experience
Reddy et al. "Clinical Experience with a Balloon Cryoablation Catheter for Pulmonary Vein Isolation in Patients with Atrial Fibrillation: One-Year Results" (abstract)
Clinical Experience
Reddy et al. "Initial Clinical Experience with a Balloon Cryoablation Catheter for Pulmonary Vein Isolation in Patients with Atrial Fibrillation" (abstract)
Clinical Experience
Rhee, Edward K. "Transcatheter Cryothermal Ablation in Pediatrics: New Technology for Old Problems" (abstract)
Pediatric clinical experience
Sarabanda et al. "Correlation Between the Outcome of Cryothermal Balloon Isolation of Pulmonary Veins and the Pathologic Findings at the Veno-atrial Junction in Dogs" (abstract)
Pre-clinical experience
Sarabanda et al. "Efficacy and Safety of Circumferential Pulmonary Vein Isolation Using a Novel Cryothermal Balloon Ablation System" (journal)
Arctic Front
Pre-Clinical Experience
Sarabanda et al. "Pulmonary Vein Remodeling and Collateral Damage with Cryothermal Balloon Ablation at the Pulmonary Vein Orifice in the Canine Heart" (abstract)
Pre-clinical experience
Skanes et al. "Isolation of Pulmonary Veins Using a Transvenous Curvilinear Cryoablation Catheter: Feasibility, Initial Experience, and Analysis of Recurrences" (journal)
Clinical Experience
Stevenson, William G. "To Freeze or Burn the Epicardium?" (editorial commentary)
Pre-clinical experience
Vogt et al. "How Effective is the Circumferential Ostial Cryoisolation of the Pulmonary Veins During Long-Term Follow-up?" (abstract)
Clinical Experience
Vogt et al. "Pulmonary Vein Stenosis After Ostial Cryoisolation in Patients with Atrial Fibrillation?" (abstract)
Clinical Experience
2004
2003
2002
2001
2000
1999